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Entries tagged as ‘Free Radicals’

Anti-oxidants, their role in our body

4 March, 2009 · Leave a Comment

This is an introductory article on Anti-oxidants. In order to grasp the role of anti-oxidants within the body, it is important to understand Free Radicals and their relationship with Anti-oxidants.

Free Radicals

Research links Free Radicals with a variety of degenerative diseases, ranging from arthritis, circulatory diseases and emphysema to asthma, allergies and eczema.Free Radicals are vital in the body’s energy production processes and are hence essential to every activity of life from movement and growth to the resistance of disease and infection and the transmission of nervous impulses.

The role of Free Radicals in Metabolism

We need to first look a little at the chemical make-up of the body. The body is comprised of cells consisting of molecules. Molecules are comprised of atoms containing electrons. A stable (neutral) molecule contains pairs of electrons. Where a molecule has one or more unpaired electrons, it is electrically unstable and is known as a free oxygen radical.Energy is produced in minute structures within the cell called mitochondria. Metabolism occurs where, in an effort to balance its electrical charge, a free radical grabs an electron from another molecule. Hence, when an electron is removed from one molecule (or oxidised) and added to another (or reduced), energy is created. The energy is then stored in enzymes called ATP and is ready for release as required.

Free Radicals on the Loose

Although Free Radicals are essential to life, without adequate control, they will escape from the mitochondria and then start to attack the tissue of cell membranes and proteins in an attempt to regain their “complete” form. This can result in a chain of oxidation, damaging up to 200,000 molecules.The results of damage to cell membranes (the damage is known as peroxidation) can be quite devastating, including an accumulation of toxic waste products in the cells, a reduction of electrical potential, a decline in vitality, an inability to repair itself effectively and a reduction in the efficiency of the immune system.

Surplus of Free Radicals

Although a certain number of Free Radicals are naturally present in the body, their production can be increased by today’s modern lifestyle and environmental factors such as sunlight and pollution. Over-eating, emotional stress or illness, cigarette smoke, poor nutrition, radiation and ultra-violet light can all lead to over-production of Free Radicals, resulting in an accumulation of toxic residues in our body tissues.American scientist, Elmer Granton MD, reports in the Journal of Holistic Medicine:

“When Free Radicals in living tissues exceed safe levels, the result is cell destruction, malignant mutation, tumour growth, damage to enzymes and inflammation. These are manifested clinically as age-related, chronic degenerative diseases. Each uncontrolled Free Radical has a potential to multiply a million-fold. Yet when functioning properly, our Anti-oxidant systems suppress excessive Free Radical reactions.”

Anti-oxidants, Nutrition and Disease

The enzymes which deactivate and destroy Free Radicals include catalase, superoxide dismutase (SOD) and glutathione peroxidase. They are heavily dependent upon anti-oxidants which are found in natural foods.

Research has shown the importance of nutrition in fighting disease; Danish Researchers at the Institute of Hygiene in Arhus found that sufferers of Multiple Sclerosis had low Anti-oxidant levels and that supplements of Selenium with Vitamins C & E were helpful (source: Biology Trace Elements Research 1990).There is a strong relationship between heart disease and Vitamins C & E. In “The Lancet” September ‘91, a report stated that men most at risk from angina had low levels of Vitamins C, E and betacarotene in their blood.

So those in the past who have used fresh, raw foods to treat a staggering range of illness including cancer, were in fact harnessing the power of anti-oxidants present in these foods. The Swiss Dr Bircher-Benner who persuaded his reluctant patients to eat raw fruit by disguising it with Muesli and the German doctor Max Gerson who used a tough regime based on raw foods as a highly successful treatment for cancer, were in fact working on the principle only recently accepted medically, that given the right tools, the body will heal itself.

Anti-oxidant power can also be enhanced simply by eating less and eating better quality food. By cutting the metabolic rate in this way, the activity of free radicals is reduced.

This brings us to the use of anti-oxidants against a world-wide range of diseases.

Anti-oxidants

The following are anti-oxidants: Vitamin A, Beta-Carotene, Vitamin B group, Vitamin E, Vitamin C, Zinc, Selenium and Potassium.We will look at each of these in turn in subsequent issues, and in particular, their anti-oxidant properties.

However, see the table below for food sources:

Vitamin A (or Beta Carotene) Milk, butter, eggs, liver, fish, fish oils, carrots, watercress, spinach, darker outer leaves of cabbage, lettuce, kale, broccoli, corn, cherries, water melon, apricots, peaches
Vitamin B Group (especially B1, B2, B3, B5, B6) Whole cereals including brown rice, oats, wholemeal wheat germ, bread, molasses, brewer’s yeast, split peas, soy-beans, sunflower seeds, ham, beef, offal especially liver, eggs
Vitamin C All fruits, especially citrus, blackcurrants, strawberries, papaya, tomatoes, all vegetables – especially green pepper. Watercress, milk, chicken liver, fresh fruit, vegetable juices
Vitamin E Cold-pressed oils, whole cereals including brown rice, oats, wholemeal bread/wheatgerm, parsley, broccoli, asparagus, spinach, outer cabbage leaves, nuts, seeds, eggs, corn, carrots
Zinc Meats, especially liver, fish, especially shellfish, lentils, green leafy vegetables, whole cereals, including wheat germ, brewer’s yeast, cheese, milk, nuts, sunflower and sesame seeds.
Selenium Whole cereals including wheat germ, meats especially offal, vegetables, fruits, milk, garlic, nuts, cold-pressed oils, eggs, a few types of brewer’s yeast.
Protein (building blocks of protein are amino acids, of which cysteine, methionene and glutathione are antioxidants) Milk, yoghurt, cheese, eggs, meat, fish, cereals and grains, nuts and seeds, peas, beans, lentils, some in other plant foods.

Categories: Antioxidants
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Can tomato lycopene help maintain health and wellbeing?

5 November, 2008 · 1 Comment

Lyc-O-Mato is an unlicensed supplement containing standardised tomato lycopene extracted from a specially bred variety of tomatoes. Lycopene, the natural pigment responsible for the beautiful red colour of tomatoes is a powerful antioxidant, at least twice as effective as beta-carotene in the body’s defence against harmful free-radicals.

Lycopene has been recognised for some time as a vital nutrient. It is the predominant carotenoid found in the blood and in various organs and tissues in the human body. Its valuable antioxidant properties protect the body against the signs of aging and the onset of chronic degenerative conditions such as heart disease, cancer and arthritis. Tomatoes (Lycopersicon esculentum) and processed tomato products are the most abundant sources of lycopene, but it is also found to a lesser degree in pink grapefruit, watermelon, guava and rosehip.

In the past, the lycopene content of ordinary tomatoes was too low to make its extraction commercially viable. This problem was solved by Israeli company LycoRed, who developed their own organically grown hybrid tomato with a lycopene content up to four times higher than normal tomatoes. Even so, it still takes two tons of these lycopene-rich tomatoes to produce a single gram of the lycopene extract, which is then mixed with tomato oil, beta carotene and vitamin E for better absorption and even more potent antioxidant effects.

Scientific Research Findings

Other items of interest

The health benefits of lycopene have been the subject of much scientific research and are well-catalogued. Below we have summarised just some of the findings:-

  • Several population studies have shown that a high intake of tomato-based foods is associated with a lower risk of cancers of the stomach, colon, rectum and prostate.
  • Following a six-year study by Harvard Medical School of 48,000 men, it was estimated that eating tomato products just twice a week (as opposed to not at all) reduced the risk of prostate cancer by up to a staggering 34%. Of 46 fruits and vegetables evaluated in the study, only the tomato showed a significant relationship with reduction in the risk of prostate cancer. Edward Giovannucci MD, who led the research said “These findings suggest that intake of lycopene or other compounds in tomatoes may reduce prostate cancer risk.”
  • A study by the Karmanos Cancer Institute in Detroit demonstrated signs of regression and decreased malignancy in the tumours of prostate cancer patients who took natural lycopene supplements.
  • Another study, conducted by the University of North Carolina, compared fat samples from men who had suffered a heart attack with those of healthy men. It found that those with high levels of lycopene were half as likely to have an attack as those with low levels.
  • Age-related macular degeneration (ARMD) is the most common form of blindness for elderly people in the western world. Lycopene is the only micro-nutrient whose serum level is shown to be inversely related to the risk of ARMD.

Take a look at Lyc-o-mato, the the original natural tomato lycopene to help maintain health and well-being.

Jemma Morriss

Categories: General Food
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Public enemy No 1 – free radicals

21 October, 2008 · Leave a Comment

What are free radicals, how do we combat them, and who is the superhero around here?

Free Radicals are pesky little varmints that lurk everywhere waiting to get through our bodies defense systems. Once on the inside, they will damage our organs and our cells health, and cause premature aging, sap our energy and stamina and whatever other damage they can manage in our immune system.

In fact, oxidative stress (stress from free radicals) is thought to contribute to the development of some heavy duty diseases and illnesses like cardiovascular disease, alzheimer’s disease, rheumatoid arthritis and neuro-degeneration, so this is serious stuff. It is in effect like our bodies rusting away on the inside.

Where do the free radicals come from?

Even the air we breathe creates the free radicals in our bodies! As does exercise. And we should exercise. Free radicals come basically from too much oxygen. Yes, we need some, but too much is a bad thing, and have you tried living without oxygen?
Our bodies are well equipped though, nature knew we were going to have this fight on our hands, but most of us can’t keep up the defense long term. Our modern, western lifestyle doesn’t do us any favours in this respect.

We need extra help, enter our superhero – Antioxidants

Antioxidants are the free-radical inhibitors which prevent damage to our systems by oxidation. They include molecules like vitamins C and E as well as certain enzymes (you may of heard of superoxide dismutase?) or phenols . You can get antioxidants from many foods including grapes (particularly the seeds and the skin); berries, especially goji berries, acai berries, blueberries and blackberries but all edible berries are good; apples; cherries; pomegranates, tea including black, green and white teas; cacao nibs, garlic, and oregano. Organic fresh fruit and veg also contribute here as many have vitamin C, beta carotene or polyphenols. So consume these in plentiful amounts to aid your defence mechanisms.

If you feel your body may need some help

If you feel your body needs a little help there are so many supplements available, or the above foods specially formulated or concentrated to help boost our antioxidant intake. Take tea for example, you can get a green tea supplement which will concentrate the polyphenols from tea giving us meaningful amounts in a pill. More effective than the odd cup of rosy lee.

Do you need more antioxidants?

We should all try and consume foods rich in antioxidants, and as I have mentioned there are plenty around. But if you smoke or take an omega 3 supplement, if you have cardiovascular or diabetes problems in your family you would be well advised to ensure your intake of antioxidants is abundant.

GoodnessDirect

Categories: Antioxidants
Tagged: ,

Broccoli stopping aging now too?

11 March, 2008 · Leave a Comment

Daily Mail: Broccoli is well known for it’s anti-cancer abilities but now has reported to possible help slow aging too.

New research shows that sulforaphane which is found in broccoli activates antioxidant genes and enzymes in immune cells.

Oxidative damage is thought to be the main cause of aging. Antioxidants prevent free radicals (supercharged oxygen) from causing this damage.

“In particular, our study shows that a chemical present in broccoli is capable of stimulating a wide range of antioxidant defence pathways and may be able to interfere with the age-related decline in immune function.”

Fresh organic broccoli at GoodnessDirect.

Categories: Antioxidants
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The humble super-tomato

11 February, 2008 · Leave a Comment

Telegraph: A new contender fights it’s way through the familiar super-food line-up – the humble tomato.
Pomegranates, pumpkin seeds, green tea, goji berries and beetroot have all jostled for position at the top of the superfood tree but it is the simple tomato that has high levels of beta-carotene (an antioxidant), antioxidant flavonoids and vitamin E, both of which are essential for heart health, and are a good source of potassium.

One medium-size tomato provides 50 per cent of vitamin C RDA, and they are high in dietary fibre and have a low glycaemic index.

Tomatoes are also the richest source of lycopene – the pigment that gives them their deep red colour. A single lycopene molecule can neutralise 13 free radicals – that’s twice power of beta-carotene, another powerful antioxidant.

See GoodnessDirect for fresh tomatoes

Categories: Antioxidants
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Life-saving Broccoli

22 January, 2008 · 1 Comment

The Telegraph reports that steamed broccoli can help you fight off cell damage and reduce the risk of a heart attack and that those who eat it are found to be at a lower risk of heart disease and some cancers.

Free radicals which are produced in our normal biological processes can reach excessive levels and harm cells and trigger cancers but the brassica family of vegetables, including cauliflower, broccoli, cabbage and Brussels sprouts, contain antioxidants which stop the build-up of these free radicals.

A new study from Journal of Agricultural and Food Chemistry, confirms these findings which were previously unconfirmed in other studies.

Another warning though: Don’t over-cook your vegetables! If broccoli is over-cooked, it loses it’s protective properties.

Categories: Antioxidants
Tagged:

Public enemy No 1 – free radicals

28 February, 2007 · Leave a Comment

Free Radicals

Free Radicals are pesky little varmants that lurk everywhere waiting to get through our bodies defence systems. Once on the inside, they will damage our organs and our cells health, and cause premature ageing, sap our energy and stamina and whatever other damage they can manage in our immune system. In fact oxidative stress (stress from free radicals) is thought to contribute to the development of some heavy duty diseases and illnesses like cardiovascular disease, alzheimer’s disease, rheumatoid arthritis and neurodegeneration, so this is serious stuff. It is in effect like our bodies rusting away on the inside.

Where do the free radicals come from?

Even the air we breathe creates the free radicals in our bodies! As does excersize. And we should excersize. Free radicals come basically from too much oxygen. Yes, we need some, but too much is a bad thing, and have you tried living without oxygen?
Our bodies are well equipped though, nature knew we were going to have this fight on our hands, but most of us can’t keep up the defence long term. Our modern, western lifestyle doesn’t do us any favours in this respect.

We need extra help, enter our superhero – Antioxidants

Antioxidants are the free-radical inhibitors which prevent damage to our systems by oxidation. They include molecules like vitamins C and E as well as certain enzymes (you may of heard of superoxide dismutase?) or phenols . You can get antioxidants from many foods including grapes (particularly the seeds and the skin); berries, especially goji berries, acai berries, blueberries and blackberries but all edible berries are good; apples; cherries; pomegranates, tea including black, green and white teas; cacao nibs, garlic, and oregano. Organic fresh fruit and veg also contribute here as many have vitamin C, beta carotene or polyphenols. So consume these in plentiful amounts to aid your defence mechanisms.

If you feel your body may need some help there are so many supplements available, or the above foods specially formulated or concentrated to help boost our antioxidant intake. Take tea for example, you can get a green tea supplement which will concentrate the polyphenols from tea giving us meaningful amounts in a pill. More effective than the odd cup of rosy lee.

Do you need help?

We should all try and cosume foods rich in antioxidants, and as I have mentioned there are plenty around. But if you smoke or take an omega 3 supplement, if you have cardiovascular or dieabetes problems in your family you would be well advised to ensure your intake of antioxidants is abundant.

Categories: Antioxidants
Tagged: ,